Quinolines and derivatives
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Filtered Search Results
Medchemexpress LLC Dosimertinib-d5 mesylate | 2403760-72-3 | 99.4% | C29H32D5N7O5S | 10MG
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Dosimertinib-d5 mesylate is the deuterated mesylate salt of dosimertinib, a third-generation epidermal growth factor receptor (EGFR) inhibitor. Provided as a research-grade reference standard for preclinical and analytical applications; not for human or veterinary use.
- Deuterated internal standard for analytical assays and mass spectrometry.
- High purity: 99.4%.
- Molecular formula: C29H32D5N7O5S.
- Available in small pack sizes (1-100 mg) suitable for method development.
- Mesylate salt form for improved handling and stability.
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Medchemexpress LLC Almonertinib mesylate | 2134096-06-1 | 99.7% | 621.75 | 25 MG
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Almonertinib mesylate (HS-10296 mesylate) is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. It shows great inhibitory activity against T790M, T790M/L858R, and T790M/Del19 (IC50: 0.37, 0.29, and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). It is used for the research of non-small cell lung cancer, and can also inhibit other EGFR sensitive mutations, including G719X, del19, L858R, and L861Q.
- Orally available
- Irreversible
- Third-generation EGFR tyrosine kinase inhibitor
- High selectivity for EGFR-sensitizing and T790M resistance mutations
- Great inhibitory activity against T790M, T790M/L858R and T790M/Del19
- Used for research of non-small cell lung cancer
- Inhibits EGFR sensitive mutations (G719X, del19, L858R, L861Q)
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Medchemexpress LLC Deferoxamine (mesylate) (Standard) | 138-14-7 | 99.8% | 25 MG
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Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator that binds to Fe(III) and many other metal cations. It is widely used to reduce iron accumulation and deposition in tissues. It upregulates HIF-1α levels with good antioxidant activity and also shows anti-proliferative activity, inducing apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases, as well as anti-cancer and anti-COVID-19 research.
- Binds to Fe(III) and many other metal cations.
- Reduces iron accumulation and deposition in tissues.
- Upregulates HIF-1α levels.
- Exhibits good antioxidant activity.
- Shows anti-proliferative activity.
- Induces apoptosis and autophagy in cancer cells.
- Used in studies of diabetes and neurodegenerative diseases.
- Used in anti-cancer and anti-COVID-19 research.
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Medchemexpress LLC Phentolamine mesylate | 65-28-1 | 99.9% | 500 MG
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Phentolamine mesylate is a reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptors. It expands blood vessels to reduce peripheral vascular resistance and can be used for the research of pheochromocytoma-related hypertension, heart failure, and erectile dysfunction.
- Reversible, non-selective, and orally active blocker of α1 and α2 adrenergic receptors
- Expands blood vessels to reduce peripheral vascular resistance
- Used for research in pheochromocytoma-related hypertension, heart failure, and erectile dysfunction
- High purity of 99.9%
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Medchemexpress LLC Dihydroergotamine mesylate | 6190-39-2 | 99.9% | 25 MG
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Dihydroergotamine mesylate is a BBB-permeable ergot alkaloid primarily used for the research of migraines.
- Decreases cell survival in A549 and NCI-H226 cells.
- Inhibits cell survival in Hep3B, PLC/PRF/5, Huh7, and HepG2 cells.
- Induces mitochondrial dysfunction and apoptosis in A549 cells.
- Inhibits STAT3 activation and enhances Mcl-1 protein stability.
- Reduces tumor growth in xenografted mouse models when combined with other agents.
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Medchemexpress LLC Deferoxamine mesylate (Standard) | 138-14-7 | 99.47% | 100 MG
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Deferoxamine mesylate (Standard) is the analytical standard for Deferoxamine mesylate, intended for research and analytical applications. It is an iron chelator, binding to Fe(III) and other metal cations, and is widely used to reduce iron accumulation and deposition in tissues. It also upregulates HIF-1α levels with good antioxidant activity, shows anti-proliferative activity, and can induce apoptosis and autophagy in cancer cells. This compound can be used in studies related to diabetes, neurodegenerative diseases, anti-cancer research, and anti-COVID-19 research.
- The compound is an analytical standard, serving as a reference standard for assays.
- Commonly employed in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
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Ambeed AMBEED
5000948929 5-METHYLQUINOLINE-3-CARBO 50MG
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Ambeed AMBEED
5000950088 1-ACETYLINDOLINE-5-CARBO 100MG
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Aobchem (4-Bromo-3-(morpholine-4-carbonyl)phenyl)boronic acid | 97% | C11H13BBrNO4 | 250mg
(4-Bromo-3-(morpholine-4-carbonyl)phenyl)boronic acid | 97% | C11H13BBrNO4 | 250mg
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Aobchem 2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 5g
2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 5g
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Aobchem 2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 1g
2 2-Difluoroethylmethane sulfonate | ≥95% | CAS 163035-65-2 | C3H6F2O3S | 1g
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Aobchem 2 3-Dihydrobenzofuran-7-carbaldehyde | 95% | CAS 196799-45-8 | C9H8O2 | 250mg
2 3-Dihydrobenzofuran-7-carbaldehyde | 95% | CAS 196799-45-8 | C9H8O2 | 250mg
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Apexbio Technology LLC Diphenidol HCl 3254-89-5 200mg
Diphenidol hydrochloride (CAS 3254-89-5) is a small molecule that acts as a nonselective antagonist of muscarinic acetylcholine receptors targeting subtypes M1 through M4 It also inhibits multiple voltage-gated ion channels including sodium (Na ) potassium (K ) and calcium (Ca ) channels thereby modulating neuronal excitability Diphenidol hydrochloride has demonstrated antiarrhythmic activity and is frequently employed in studies investigating the neurophysiological mechanisms underlying vertigo and the pathways involved in antiemetic responses Its polypharmacological profile makes it a suitable tool for research into neural signaling and emesis modulation
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eMolecules 303085-53-2 | 6-Chloropyridazine-3-carbaldehyde | Ambeed | MFCD10698041 | 142.540 | C5H3ClN2O | 95.000 | Clc1ccc(C=O)nn1 | 1g | 528956450
6-Chloropyridazine-3-carbaldehyde | Ambeed | 303085-53-2 | MFCD10698041 | 142.540 | C5H3ClN2O | 95.000 | Clc1ccc(C=O)nn1 | 1g | 528956450
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eMolecules 88950-64-5 | 1-Aminocyclopropane-1-carboxylic acid, N-BOC protected | Apollo Scientific | MFCD00083257 | 201.222 | C9H15NO4 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C(O)=O | 1g | 600855395
1-Aminocyclopropane-1-carboxylic acid, N-BOC protected | Apollo Scientific | 88950-64-5 | MFCD00083257 | 201.222 | C9H15NO4 | 97.000 | CC(C)(C)OC(=O)NC1(CC1)C(O)=O | 1g | 600855395
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